Lemanske R, Mauger D, Sorkness C, Jackson D, Boehmer S, Martinez F, Strunk R, Szefler S, Pointer R, Bach Aryans L, Covar R, Guilbert T, Larsen G, Morgan W, Spahn J, Taussig L. Step-up asthma Care in Children Uncontrolled on inhaled corticosteroids. New England Journal of Medicine Online First, March 2010.
To treat children whose asthma is not well controlled, while attempting to low-dose inhaled corticosteroids, the National Heart, and Blood Institute guides physicians to an additional three or step-up, treatments:. Doubling the dose of inhaled corticosteroid or adding a long-acting beta antagonist or a leukotriene receptor antagonist are treated for inhaled corticosteroids. Read More